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Lena Witzdam, M.Sc.

Ph.D. student

Lena Witzdam works on the development of adaptive hemocompatible coatings for medical applications. The coatings are engineered to passively prevent thrombus formation by modification with polymer brushes but are also able to communicate with blood and direct it in a self-regulated manner. The inspiration for this is nature and the mechanisms used by the body to achieve a balance between clotting and fibrinolysis. 




Green Solvent-Based Antifouling Polymer Brushes Demonstrate Excellent Hemocompatibility

Englert, J.; Palà, M.; Witzdam, L.; Rayatdoost, F.; Grottke, O.; Lligadas, G.; Rodriguez-Emmenegger, C.

Langmuir, 39 (50), 18476–18485. (2023)

Brush-Like Coatings Provide a Cloak of Invisibility to Titanium Implants

Witzdam, L.*; Garay-Sarmiento, M.*; Gagliardi, M.; Meurer, Y. L.; Rutsch, Y.; Englert, J.; Philipsen, S.; Janem, A.; Alsheghri, R.; Jakob, F.; Molin, D.G M.; Schwaneberg, U.; van den Akker, N.; Rodriguez-Emmenegger, C.

Macromolecular Bioscience, 202300434. (2023)

* equal contributions

Synthetic evolution of a supramolecular harpooning mechanism to immobilize vesicles at antifouling interfaces

Englert, J.*; Witzdam, L.*; Söder, D.; Garay-Sarmiento, M; Joseph, A.; Wagner, A. M.; Rodriguez-Emmenegger, C.

Macromolecular Chemistry and Physics, 202300306. (2023)

* equal contributions

Tackling the Root Cause of Surface‐Induced Coagulation: Inhibition of FXII Activation to Mitigate Coagulation Propagation and Prevent Clotting

Witzdam, L.; Vosberg, B.; Große-Berkenbusch, K.; Stoppelkamp, S.; Wendel, H. P.; Rodriguez-Emmenegger, C.

Macromolecular Biosciene, 202300321. (2023)

Interactive Hemocompatible Nanocoating to Prevent Surface‐Induced Coagulation in Medical Devices

Quandt, J.*; Garay-Sarmiento M.*; Witzdam, L.; Englert, J.; Rutsch, Y.; Stöcker, C.; Grottke, O.; Rodriguez-Emmenegger, C.

Advanced Materials Interfaces, 9 (33), 2201055. (2022)

* equal contributions

Ionic Combisomes: A New Class of Biomimetic Vesicles to Fuse with Life

Wagner, A. M.*; Quandt, J.*; Söder, D.; Garay-Sarmiento, M.; Joseph, A.; Petrovskii, V. S.; Witzdam, L.; Hammoor, T.; Steitz, P.; Haraszti, T.; Potemkin, II; Kostina, N. Y.; Herrmann, A.; Rodriguez-Emmenegger, C.

Advanced Science, 9, 2200617. (2022)

* equal contributions

Brush-Like Interface on Surface-Attached Hydrogels Repels Proteins and Bacteria

Witzdam, L.*; Meurer, Y. L.*; Garay‐Sarmiento, M.; Vorobii, M.; Söder, D.; Quandt, J.; Haraszti, T.; Rodriguez-Emmenegger, C.

Macromolecular Bioscience, 22 (5), 2200025. (2022)

* equal contributions

Kill&Repel Coatings: the marriage of antifouling and bactericidal properties to mitigate and treat wound infections

Garay‐Sarmiento, M.; Witzdam, L.; Vorobii, M.; Simons, C.; Herrmann, N.; de los Santos Pereira, A.; Heine, E.; El‐Awaad, I.; Lütticken, R.; Jakob, F.; Schwaneberg, U.; Rodriguez-Emmenegger, C.

Advanced Functional Materials, 32 (9), 2106656. (2022)

Improving Hemocompatibility: How Can Smart Surfaces Direct Blood To Fight against Thrombi

Obstals, F.*; Witzdam, L.*; Garay-Sarmiento, M.; Kostina, N. Yu.; Quandt, J.; Rossaint, R.; Singh, S.; Grottke, O.; Rodriguez-Emmenegger, C.

ACS Applied Materials and Interfaces, DOI:10.1021/acsami.1c01079 (2021)

* equal contributions

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